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Explore/eye disease ophthalmology retina

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

156 results for “eye disease ophthalmology retina” · Recruiting

Page 1 of 11

Recruiting

Adaptive Optics Retinal Imaging

N/AGlaucoma, Primary Open Angle

oxygen inhalationAdaptive optics imaging

Food and Drug Administration (FDA)150 participants1 site · United StatesCompletes Sep 2028

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Recruiting

An Efficacy and Safety Study of DFL24498 in the Treatment of AKC

Phase 3Atopic Keratoconjunctivitis

DFL24498Vehicledexamethasone sodium phosphate (DSP) ophthalmic solution

Dompé Farmaceutici S.p.A138 participants19 sites · United States, Italy, SpainCompletes Mar 2027

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Recruiting

Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is Suspected

N/AOptic NeuritisOptic NeuropathyVisual Loss

First Affiliated Hospital of Guangxi Medical University500 participants9 sites · ChinaCompletes Dec 2027

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Recruiting

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

Phase 1Phase 2Rhegmatogenous Retinal DetachmentProliferative Vitreoretinopathy

Netarsudil Ophthalmic

Massachusetts Eye and Ear Infirmary48 participants1 site · United StatesCompletes Sep 2026

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Recruiting

A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma

Phase 3Choroidal MelanomaIndeterminate LesionsUveal Melanoma

Bel-sarSuprachoroidal MicroinjectorInfrared Laser+2 more

Aura Biosciences100 participants71 sites · United States, Australia, AustriaCompletes Nov 2027

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Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study

N/ARetinal DiseasesFuchs Endothelial DystrophyMacular Hole

The Cleveland Clinic3,000 participants1 site · United StatesCompletes Jan 2027

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Recruiting

EarLy Treatment Response in nEoVascular Macular Degeneration With Eylea 8mg: ELEV8 A Prospective Observational Open Label Study Investigating the Fluid Dynamics During Early Response to Aflibercept 8mg in Patients With Exudative Age-related Macular Degeneration (AMD).

N/AAge-Related Macular Degeneration (AMD)

treatment with Aflibercept 8mg (Eylea)

Insel Gruppe AG, University Hospital Bern50 participants1 site · SwitzerlandCompletes Mar 2026

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Recruiting

Electrical Stimulation for the Treatment of Optic Neuropathies

N/AGlaucomaGlaucoma, Open-AngleOptic Nerve Diseases

Repetitive, Transorbital Alternating Current Stimulation (rtACS)

Stanford University40 participants1 site · United StatesCompletes Dec 2026

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Recruiting

Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability

N/AIntellectual Disability

no intervention

National Taiwan University Hospital1,400 participants2 sites · TaiwanCompletes Jan 2027

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Recruiting

Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal Lymphoma

N/AVitreoretinal Lymphoma

Vinodh Kakkassery, MD220 participants1 site · GermanyCompletes Sep 2026

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Recruiting

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

Phase 2Phase 3Dry Eye Disease (DED)

Artificial Tear Run-inlicaminlimabVehicle of licaminlimab

Oculis160 participants14 sites · United StatesCompletes Dec 2026

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Recruiting

Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Phase 1Phase 2Age-Related Macular DegenerationGeographic AtrophyNon-neovascular AMD

VOY-101

Perceive Biotherapeutics, Inc.60 participants11 sites · United States, Australia, IsraelCompletes Jun 2027

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Recruiting

Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

Phase 3Neovascular Age-Related Macular Degeneration (nAMD)

4D-150 IVT (3E10 vg/eye)EYLEA® (aflibercept) Injection 2 mg (0.05mL)

4D Molecular Therapeutics480 participants94 sites · United States, Argentina, AustraliaCompletes Nov 2028

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Recruiting

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus

N/ADiabetesDiabetic RetinopathyType 2 Diabetes Mellitus (T2DM)

Fundus ExaminationMetabolomics analysis

Yufan Wang2,920 participants3 sites · ChinaCompletes Aug 2025

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Recruiting

Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment

Phase 4Retinal Detachment

Nicotinamide RibosidePlaceboVitrectomy and Gas tamponade

Center for Eye Research Australia144 participants5 sites · AustraliaCompletes Oct 2027

Compare CT.gov Full analysis →

1–15 of 156

Explore/eye disease ophthalmology retina

Status

Phase

Pre-filtered to show active, later-stage trials with the strongest clinical signal.

156 results for “eye disease ophthalmology retina” · Recruiting

Page 1 of 11

Recruiting

Adaptive Optics Retinal Imaging

N/AGlaucoma, Primary Open Angle

oxygen inhalationAdaptive optics imaging

Food and Drug Administration (FDA)150 participants1 site · United StatesCompletes Sep 2028

Compare CT.gov Full analysis →

Recruiting

An Efficacy and Safety Study of DFL24498 in the Treatment of AKC

Phase 3Atopic Keratoconjunctivitis

DFL24498Vehicledexamethasone sodium phosphate (DSP) ophthalmic solution

Dompé Farmaceutici S.p.A138 participants19 sites · United States, Italy, SpainCompletes Mar 2027

Compare CT.gov Full analysis →

Recruiting

Prospective Evaluation of the 2022 Optic Neuritis Criteria When Optic Neuritis Is Suspected

N/AOptic NeuritisOptic NeuropathyVisual Loss

First Affiliated Hospital of Guangxi Medical University500 participants9 sites · ChinaCompletes Dec 2027

Compare CT.gov Full analysis →

Recruiting

Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment

Phase 1Phase 2Rhegmatogenous Retinal DetachmentProliferative Vitreoretinopathy

Netarsudil Ophthalmic

Massachusetts Eye and Ear Infirmary48 participants1 site · United StatesCompletes Sep 2026

Compare CT.gov Full analysis →

Recruiting

Phase 3Choroidal MelanomaIndeterminate LesionsUveal Melanoma

Bel-sarSuprachoroidal MicroinjectorInfrared Laser+2 more

Aura Biosciences100 participants71 sites · United States, Australia, AustriaCompletes Nov 2027

Compare CT.gov Full analysis →

Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study

N/ARetinal DiseasesFuchs Endothelial DystrophyMacular Hole

The Cleveland Clinic3,000 participants1 site · United StatesCompletes Jan 2027

Compare CT.gov Full analysis →

Recruiting

N/AAge-Related Macular Degeneration (AMD)

treatment with Aflibercept 8mg (Eylea)

Insel Gruppe AG, University Hospital Bern50 participants1 site · SwitzerlandCompletes Mar 2026

Compare CT.gov Full analysis →

Recruiting

Electrical Stimulation for the Treatment of Optic Neuropathies

N/AGlaucomaGlaucoma, Open-AngleOptic Nerve Diseases

Repetitive, Transorbital Alternating Current Stimulation (rtACS)

Stanford University40 participants1 site · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

Recruiting

Development and Validation of the Observatory Battery of Common Eye Disorders for Adults With Intellectual Disability

N/AIntellectual Disability

no intervention

National Taiwan University Hospital1,400 participants2 sites · TaiwanCompletes Jan 2027

Compare CT.gov Full analysis →

Recruiting

Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal Lymphoma

N/AVitreoretinal Lymphoma

Vinodh Kakkassery, MD220 participants1 site · GermanyCompletes Sep 2026

Compare CT.gov Full analysis →

Recruiting

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

Phase 2Phase 3Dry Eye Disease (DED)

Artificial Tear Run-inlicaminlimabVehicle of licaminlimab

Oculis160 participants14 sites · United StatesCompletes Dec 2026

Compare CT.gov Full analysis →

Recruiting

Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration

Phase 1Phase 2Age-Related Macular DegenerationGeographic AtrophyNon-neovascular AMD

VOY-101

Perceive Biotherapeutics, Inc.60 participants11 sites · United States, Australia, IsraelCompletes Jun 2027

Compare CT.gov Full analysis →

Recruiting

Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

Phase 3Neovascular Age-Related Macular Degeneration (nAMD)

4D-150 IVT (3E10 vg/eye)EYLEA® (aflibercept) Injection 2 mg (0.05mL)

4D Molecular Therapeutics480 participants94 sites · United States, Argentina, AustraliaCompletes Nov 2028

Compare CT.gov Full analysis →

Recruiting

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus

N/ADiabetesDiabetic RetinopathyType 2 Diabetes Mellitus (T2DM)

Fundus ExaminationMetabolomics analysis

Yufan Wang2,920 participants3 sites · ChinaCompletes Aug 2025

Compare CT.gov Full analysis →

Recruiting

Nicotinamide Riboside Oral Supplementation in Macula Off Retinal Detachment

Phase 4Retinal Detachment

Nicotinamide RibosidePlaceboVitrectomy and Gas tamponade

Center for Eye Research Australia144 participants5 sites · AustraliaCompletes Oct 2027

Compare CT.gov Full analysis →

1–15 of 156