RECRUITINGNA

Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

The investigators are investigating whether home-based tDCS over the course of four weeks can improve ADHD symptom severity and improve dysexecutive functioning (cognitive control). Further, the investigators are investigating whether there is a dose-dependent response to tDCS.

Sponsor

Massachusetts General Hospital

Enrollment

60 participants

Sites

1 locations

Start Date

July 2022

Completion

May 2026

Attention Deficit DisorderAttention Deficit Disorder With Hyperactivity2 mA transcranial direct current stimulation (tDCS)1 mA transcranial direct current stimulation (tDCS)

Enrollment & Timeline

Recruiting

Target enrollment (estimated)

Target N

participants

Sites

locations

Duration

3.8 years

total trial span

Rate

pts/month needed

Jul 2022Month 47 of 46May 2026

100% of trial timeline elapsed

At 1 sites, each site needs to enroll approximately 1.0 patients/month to hit the enrollment target on schedule.

Enrollment target is estimated. ClinicalTrials.gov does not provide real-time enrollment progress.

View on ClinicalTrials.gov

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Primary Outcomes

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Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Deep Learning Convolutional Neural Networks Discriminate Adult ADHD From Healthy Individuals on the Basis of Event-Related Spectral EEG.

Dubreuil-Vall Laura, Ruffini Giulio, Camprodon Joan AFrontiers in neuroscience2020

DOI PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

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Fetching protocol from ClinicalTrials.gov…

RECRUITINGNA

Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Sponsor

Massachusetts General Hospital

Enrollment

60 participants

Sites

1 locations

Start Date

July 2022

Completion

May 2026

Attention Deficit DisorderAttention Deficit Disorder With Hyperactivity2 mA transcranial direct current stimulation (tDCS)1 mA transcranial direct current stimulation (tDCS)

Enrollment & Timeline

Recruiting

Target enrollment (estimated)

Target N

participants

Sites

locations

Duration

3.8 years

total trial span

Rate

pts/month needed

Jul 2022Month 47 of 46May 2026

100% of trial timeline elapsed

At 1 sites, each site needs to enroll approximately 1.0 patients/month to hit the enrollment target on schedule.

Enrollment target is estimated. ClinicalTrials.gov does not provide real-time enrollment progress.

View on ClinicalTrials.gov

Ask AI

Primary Outcomes

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Deep Learning Convolutional Neural Networks Discriminate Adult ADHD From Healthy Individuals on the Basis of Event-Related Spectral EEG.

Dubreuil-Vall Laura, Ruffini Giulio, Camprodon Joan AFrontiers in neuroscience2020

DOI PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

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P300 Amplitude during Erickson Flanker Task

Week 1 - Week 8 of Study

P300, an electrophysiological feature theorized to represent executive functioning, has been previously shown to be notably diminished during the Erickson Flanker Task (EFT) . We will be administering this task to assess changes in P300 during the EFT, and if any changes are related to subjects' assigned condition.

Global Assessment of Functioning (GAF) Scale

Week 1 - Week 8 of Study

investigators will use GAF scale to assess the potential feasibility of at-home tDCS for future research.

Adult ADHD Self-Report Scale

Week 1 - Week 8 of Study

Investigators will assess changes to these questionnaires in reference to assigned stimulation group to assess changes to ADHD symptomatology across study duration.

Eligibility

Min Age

18 Years

Max Age

65 Years

Sex

all

Healthy Volunteers

View full criteria

Inclusion Criteria:

1. Male and female outpatients 18-65 years of age
2. A diagnosis of ADD/ADHD or meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.

Exclusion Criteria:

1. Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, VP shunt, pacemakers, pregnancy.
2. Active substance dependence (except for tobacco).
3. Pregnant or nursing females.
4. Inability to participate in testing procedures.
5. Premorbid neurological conditions (including neurovascular and neurodegenerative diseases such as traumatic brain injury, stroke, Parkinson's, AD and other dementias) and severe psychiatric disorders (bipolar disorder, schizophrenia).

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Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Enrollment & Timeline

Primary Outcomes

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Enrollment & Timeline

Primary Outcomes

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Eligibility

Trial Sites (1)