COMPLETEDN/A

Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age

SARS-CoV2 or CoVid19 disease is a newly described pathology linked to a subtype of the coronavirus family identified in China in December 2019. This pathology can present multiple clinical facets, ranging from asymptomatic forms to more commonly critical pulmonary forms called "Acute Respiratory Distress Syndrome". The elderly population is more at risk for this infection due to the senescence of the immune system, co-morbidities and poly medications. They also often present a greater state of fragility. This study aims to report the epidemiology of the first 50 patients over 90 years of age hospitalized within the CHU Brugmann hospital.

Sponsor

Murielle Surquin

Enrollment

50 participants

Sites

1 locations

Start Date

June 2020

Completion

November 2020

Covid19Data collection from medical files

Enrollment & Timeline

Completed

Target N

participants

Sites

locations

Duration

5 months

total trial span

Rate

pts/month needed

At 1 sites, each site needs to enroll approximately 10.0 patients/month to hit the enrollment target on schedule.

View on ClinicalTrials.gov

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

No linked publications found in PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

Ask AI

Fetching protocol from ClinicalTrials.gov…

COMPLETEDN/A

Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age

Sponsor

Murielle Surquin

Enrollment

50 participants

Sites

1 locations

Start Date

June 2020

Completion

November 2020

Covid19Data collection from medical files

Enrollment & Timeline

Completed

Target N

participants

Sites

locations

Duration

5 months

total trial span

Rate

pts/month needed

At 1 sites, each site needs to enroll approximately 10.0 patients/month to hit the enrollment target on schedule.

View on ClinicalTrials.gov

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

No linked publications found in PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

Ask AI

Primary Outcomes

Demographic data

5 minutes

Age, sex, ethnicity

Comorbidities

5 minutes

Smoking, Obesity, Diabetes, Arterial hypertension, Coronary pathology, Cerebrovascular disease, chronic renal failure, chronic obstructive pulmonary disease, Neoplasia, Autoimmune disease, Chronic liver disease

Cumulative Illness Rating Scale-Geriatric (CIRS-G)

5 minutes

CIRS-G quantifies burden of disease in elderly patients (comorbidity scale). Higher scores indicate higher severity (maximum score = 56 points).

Treatments

5 minutes

Under Chronic corticosteroid therapy or Immunosuppressive therapy

Signs and symptoms

5 minutes

Presence and date of first apparition: Fever, Cough, Dyspnea, Chest pain, Nausea or vomiting, Diarrhea, Fatigue, Anosmia, ageusia, inappetence, Confusion, Fall, Fracture

Fever

5 minutes

Vital signs at hospital admission: Fever

Hypoxemia

5 minutes

Vital signs at hospital admission: Hypoxemia

Tachycardia

5 minutes

Vital signs at hospital admission:Tachycardia

Hypotension

5 minutes

Vital signs at hospital admission: Hypotension

Gasometry

5 minutes

Vital signs at hospital admission: Gasometry

Infectious data

5 minutes

Contact with confirmed covid person before admission, lives in a retirement home with other cases, Initial bacterial or viral co-infection, Bacterial or viral co-infection during the hospital stay

Blood count

5 minutes

Blood count at hospital admission or first recorded

Ionogram

5 minutes

Ionogram at hospital admission or first recorded

Liver function

5 minutes

Liver function at hospital admission or first recorded

Coagulation

5 minutes

Coagulation at hospital admission or first recorded

Renal function

5 minutes

Renal function at hospital admission or first recorded

Albumin

5 minutes

Albumin at hospital admission or first recorded

CRP

5 minutes

CRP at hospital admission or first recorded

Fibrinogen

5 minutes

Fibrinogen at hospital admission or first recorded

D-dimers at hospital admission or first recorded

5 minutes

D-dimers

NTproBNP

5 minutes

NTproBNP at hospital admission or first recorded

5 minutes

CK at hospital admission or first recorded

Troponin

5 minutes

Troponin at hospital admission or first recorded

Ferritin

5 minutes

Ferritin at hospital admission or first recorded

Procalcitonin

5 minutes

Procalcitonin at hospital admission or first recorded

Biology - highest rate

5 minutes

Highest rate of CRP, D-Dimers, Urea, Creatinin, Fibrinogen, CK, Troponins

Biology - lowest rate

5 minutes

Lowest rate of hemoglobin, platelets, leucocytes, lymphocytes, albumin, Na+, K+

Percentage of pulmonary involvement on chest CT scan

5 minutes

Percentage of pulmonary involvement on chest CT scan

Number of pulmonary lobes affected

5 minutes

Number of pulmonary lobes affected

Type of lesions

5 minutes

Type of lesions as reflected on the CT scan images: 'Ground glass' or 'Crazy paving'

Need for oxygenotherapy

5 minutes

Need for oxygenotherapy (yes/no)

Means of ventilation

5 minutes

Means of ventilation

Treatment received

5 minutes

Hydroxychloroquine or Azithromycin

Length of ICU Stay

5 minutes

Length of ICU Stay

Status at hospital exit

5 minutes

One of the following choices: death, went back home, went back to a retirement home, was placed in a revalidation unit.

Mortality

5 minutes

28-day mortality after PCR / CT scan / diagnosis

Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age

Enrollment & Timeline

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age

Enrollment & Timeline

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

Primary Outcomes

Eligibility

Trial Sites (1)