UNKNOWNNA

Ultrasound-Guided Serratus Plane Block Vs Paravertebral Block For Chronic Post-mastectomy Pain.

compare the analgesic efficacy between ultrasound paraverbral block and serratus block in post mastectomy pain.

Sponsor

Assiut University

Enrollment

50 participants

Sites

0 locations

Start Date

July 2020

Completion

April 2021

Post-mastectomy Pain Syndromeserratus plane block by ultra-soundparavertebral block by ultra-sound

Enrollment & Timeline

UNKNOWN

Target enrollment (estimated)

Target N

participants

Sites

locations

Duration

11 months

total trial span

Rate

pts/month needed

Jul 2020Month 73 of 11Apr 2021

100% of trial timeline elapsed

Enrollment target is estimated. ClinicalTrials.gov does not provide real-time enrollment progress.

View on ClinicalTrials.gov

Ask AI

Primary Outcomes

Percentage of patients gaining ≥ 50% pain reduction at VAS Score from baseline value.

baseline

Compare the analgesic efficacy between ultrasound paraverbral block and serratus block in chronic postmastectomy pain.

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

A retrospective cohort study of post mastectomy pain syndrome.

Smith W C, Bourne D, Squair J et al.Pain1999

DOI PubMed

Chronic pain and other sequelae in long-term breast cancer survivors: nationwide survey in Denmark.

Peuckmann V, Ekholm O, Rasmussen N K et al.European journal of pain (London, England)2009

DOI PubMed

Post-mastectomy pain syndrome: the magnitude of the problem.

Couceiro Tania Cursino de Menezes, Menezes Telma Cursino de, Valênça Marcelo MoraesRevista brasileira de anestesiologia2009

DOI PubMed

Prevalence of and factors associated with persistent pain following breast cancer surgery.

Gärtner Rune, Jensen Maj-Britt, Nielsen Jeanette et al.JAMA2009

DOI PubMed

Effectiveness of a multidimensional physical therapy program on pain, pressure hypersensitivity, and trigger points in breast cancer survivors: a randomized controlled clinical trial.

Fernández-Lao Carolina, Cantarero-Villanueva Irene, Fernández-de-Las-Peñas César et al.The Clinical journal of pain2012

DOI PubMed

Neural blockade for persistent pain after breast cancer surgery.

Wijayasinghe Nelun, Andersen Kenneth G, Kehlet HenrikRegional anesthesia and pain medicine2015

DOI PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

Ask AI

Fetching protocol from ClinicalTrials.gov…

UNKNOWNNA

Ultrasound-Guided Serratus Plane Block Vs Paravertebral Block For Chronic Post-mastectomy Pain.

compare the analgesic efficacy between ultrasound paraverbral block and serratus block in post mastectomy pain.

Sponsor

Assiut University

Enrollment

50 participants

Sites

0 locations

Start Date

July 2020

Completion

April 2021

Post-mastectomy Pain Syndromeserratus plane block by ultra-soundparavertebral block by ultra-sound

Enrollment & Timeline

UNKNOWN

Target enrollment (estimated)

Target N

participants

Sites

locations

Duration

11 months

total trial span

Rate

pts/month needed

Jul 2020Month 73 of 11Apr 2021

100% of trial timeline elapsed

Enrollment target is estimated. ClinicalTrials.gov does not provide real-time enrollment progress.

View on ClinicalTrials.gov

Ask AI

Primary Outcomes

Percentage of patients gaining ≥ 50% pain reduction at VAS Score from baseline value.

baseline

Compare the analgesic efficacy between ultrasound paraverbral block and serratus block in chronic postmastectomy pain.

Ask AI

Multi-Source Intelligencefrom PubMed · FDA FAERS · WHO ICTRP

A retrospective cohort study of post mastectomy pain syndrome.

Smith W C, Bourne D, Squair J et al.Pain1999

DOI PubMed

Chronic pain and other sequelae in long-term breast cancer survivors: nationwide survey in Denmark.

Peuckmann V, Ekholm O, Rasmussen N K et al.European journal of pain (London, England)2009

DOI PubMed

Post-mastectomy pain syndrome: the magnitude of the problem.

Couceiro Tania Cursino de Menezes, Menezes Telma Cursino de, Valênça Marcelo MoraesRevista brasileira de anestesiologia2009

DOI PubMed

Prevalence of and factors associated with persistent pain following breast cancer surgery.

Gärtner Rune, Jensen Maj-Britt, Nielsen Jeanette et al.JAMA2009

DOI PubMed

Effectiveness of a multidimensional physical therapy program on pain, pressure hypersensitivity, and trigger points in breast cancer survivors: a randomized controlled clinical trial.

Fernández-Lao Carolina, Cantarero-Villanueva Irene, Fernández-de-Las-Peñas César et al.The Clinical journal of pain2012

DOI PubMed

Neural blockade for persistent pain after breast cancer surgery.

Wijayasinghe Nelun, Andersen Kenneth G, Kehlet HenrikRegional anesthesia and pain medicine2015

DOI PubMed

PubMed/NCBI (daily updates) FDA FAERS (quarterly updates) WHO ICTRP (weekly updates)

Ask AI

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

female

Healthy Volunteers

View full criteria

Inclusion Criteria:

* Patients have postmastectomy pain of neuropathic nature, DN4

  * 4 for at least 3ms duration.
* The intensity of postmastectomy pain on VAS score ≥ 5.
* Unsatisfactory treatment with 1st line antineuropathic drugs, Pregabalin(150 mg daily) or Deloxetine(60mg daily).

Exclusion Criteria:

* Infection of the skin at or near site of needle puncture.
* Coagulopathy .
* Drug hypersensitivity or allergy to the studied drugs.
* Central or peripheral neuropthy .
* Significant organ dysfunction .
* Morbid obesity (BMI\>35kg/m2) .
* Vertebral anomalies.