This study will evaluate the pharmacokinetics of ridaforolimus including the area under the concentration-time curve (AUC\[0-infinity\]) and maximum concentration (Cmax) after administration of a single dose of ridaforolimus in patients with moderate hepatic insufficiency and healthy matched control subjects.
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Inclusion Criteria: Hepatic Patients: * Female patient is of non-child bearing potential * Apart from hepatic insufficiency with features of cirrhosis, patient is otherwise in good health * Patient has a diagnosis of chronic stable hepatic insufficiency with features of cirrhosis Healthy Subjects: * Female subject is of non-childbearing potential * Subject is in good health Exclusion Criteria: Hepatic Patients and Healthy Subjects: * Works a night shift and is not able to avoid night shift work during the study * Has a history of stroke, seizure or major neurological disease * Has a history of cancer * Is unable to refrain from or anticipates the use of any prescription or non-prescription drugs during the study * Consumes excessive amounts of alcohol or caffeine * Has had major surgery, donated blood or participated in another investigational study in the past 4 weeks