To determine if platelet dysfunction and/or pharmacologic drug interaction occurs in patients taking both AZT and ibuprofen, which might account for enhanced bleeding tendency.
Inclusion Criteria Patients must have: * Hemophilia. * HIV-seropositivity confirmed by Western Blot. Prior Medication: Required: \- AZT for study patients. Allowed: \- Ibuprofen. Exclusion Criteria Co-existing Condition: Patients with the following symptoms and conditions are excluded: Hospitalization for opportunistic infection, bacterial infection or malignancy. Concurrent Medication: Excluded: * AZT (for control group). * Antibiotics or other medication for opportunistic infection, bacterial infection, or malignancy. Patients with the following prior conditions are excluded: Hospitalization for opportunistic infection, bacterial infection, or malignancy. Required: * Ibuprofen. * AZT 1-2 gm daily (for study patient) or not taking AZT (for control).